Detection of Out-of-Focus Regions
Precise focusing is one of the important parameters to obtain high-quality images. Unfortunately, whole slide images produced by commercial scanners may result in out-of-focus areas. The main reason for the blurred images is the improper focusing on the tissue. Although the scanners are able to calculate the precise focusing parameter for a specific point, the regions between two focus points can be out-of-focus due to the 3d structure of the tissue.